Chemical Biologist

Guidehouse · BETHESDA, MD, United States

Location
BETHESDA
Job Type
Full-time
Posted
June 18, 2026

Job Description

**Job Family** **:**

Scientist

**Travel Required** **:**

None

**Clearance Required** **:**

Ability to Obtain Public Trust

**What You Will Do** **:**
We are currently searching for a Chemical Biologist to provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute (NHLBI).  This is a full-time, on-site opportunity in Bethesda, MD.

+ Synthesize and optimize small cyclic peptides for diagnostic imaging and early-stage drug discovery applications.

+ Design and develop small molecules as chemical tools to support biological research, including target validation and imaging (MRI, optical, PET).

+ Develop and implement mRNA-based peptide expression systems for cyclic peptide production.

+ Perform peptide conjugation, including linking to fluorescent dyes, chelators, or imaging agents.

+ Prepare and characterize antibody fragments...

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