Downstream Purification Scientist

Cynet Systems · Boston, Massachusetts, United States

Location
Boston
Job Type
Full-time
Posted
June 16, 2026

Job Description


Job Description:

Pay Range: $40.41hr - $45.41hr
  • The Downstream Purification Scientist will be responsible for executing and optimizing purification processes for viral vectors and related biologics.
  • This role involves hands-on operation of chromatography systems, ultracentrifugation, and tangential flow filtration (TFF) while supporting process development and documentation in compliance with GMP/GLP standards.
  • The ideal candidate will collaborate cross-functionally to ensure high-quality purification and product characterization.
  • Responsibilities:
  • Execute purification processes including CsCl density gradient ultracentrifugation, affinity chromatography (AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and polishing steps.
  • Operate AKTA systems (Avant, Pure, or Pilot) for small- to large-scale purification runs.
  • Perform TFF operations for buffer exchange and concentration of interme...
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