PhD in Advanced in vitro modeling and biomechanical characterization of intravasation

Introduction

Are you eager to work on the development and experimental analysis of advanced microphysiological models that can help us understand how cancer spreads throughout the body? In our research team, we aim to understand a crucial step in cancer spreading: how cancer cells move into blood vessels.

Job Description

Cancer still is one of the worlds deadliest diseases. Most devastating is the ability of cancer cells to spread throughout the body in a multistep process called metastasis, the major cause for mortality. A critical step is intravasation, when cancer cells pass a blood vessel wall to enter the blood stream, and travel to another location to create a secondary tumor. However, the mechanisms of intravasation are still largely unexplored, even though it is pivotal: if we can prevent it, cancer does not spread. In the ERC-AdG research project Intrap, we aim to enhance our understanding of intravasation through a unique exper...