Postdoctoral Fellow-MSH-30025-250

**Job Description**

The Izzo Lab (Laboratory of Clonal Evolution and Molecular Epigenetics of Cancer) at the Icahn School of Medicine at Mount Sinai is seeking a highly motivated **Postdoctoral Fellow in Bioinformatics** to join our team. Our research focuses on uncovering the fundamental mechanisms driving the onset, therapy resistance, and progression of hematological malignancies, with a particular emphasis on **clonal evolution** , **genetic heterogeneity** , and **epigenetic plasticity** . We develop and apply cutting-edge **single-cell sequencing technologies** (including multi-omic approaches integrating genomics, transcriptomics, and epigenomics) to directly profile patient samples. This work aims to map genotype-to-phenotype relationships, understand how somatic mutations drive epigenetic deregulation, and identify vulnerabilities that can be targeted to overcome therapy resistance and improve patient outcomes. The successful candidate will play a central role ...