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Scientist, Laboratory of Precision Disease Therapeutics (GIS)

A*STAR · Singapore, Singapore, Singapore

Location
Singapore
Job Type
Full-Time
Posted
June 17, 2026

Job Description

We seek a PhD-trained scientist with expertise in early drug discovery for metabolic diseases, with several years of experience (ASO/siRNA therapeutic modality is preferred), target validation, and MASH research. Demonstrated ability to lead and execute discovery projects in both in-house and CRO-based settings, ensuring high-quality data delivery and efficient project progression.


Core Competencies:

  • Drug Discovery Expertise: Strong track record in early discovery, from target identification to validation, hit-to-lead and preclinical assessment.

  • RNA Therapeutics (preferred): Hands-on expertise with ASO and siRNA platforms, including design, in vitro/in vivo validation, and optimization for metabolic disease applications.

  • Target Validation & Disease Biology: Experienced in establishing mechanistic links between targets and disease biology, with emphasis on MASH and metabolic disorders.

  • Working with CROs: Effective in managing CRO ...

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