Senior Analytical Scientist (Method Development & Platform Innovation) – Contract position

Government Technology Agency (GovTech) · singapore, singapore, Singapore

Location
singapore
Job Type
Full-time
Posted
June 17, 2026

Job Description

What the role is

To lead the development, optimization, and validation of bioassays and advanced analytical methodologies to support the regulatory testing of monoclonal antibodies (mAbs) and next‑generation formats (ADCs, bispecifics, scFvs, AOCs etc.) to ensure the quality and safety of innovator and biosimilar products in the market.

What you will be working on

Technical Excellence & Method Development: Lead bioassay development for monoclonal antibodies and next‑generation complex formats (ADCs, bispecifics, scFvs, AOCs etc.) that reflect functionality including ADCC/CDC assays, dual‑target engagement, payload‑mediated cytotoxicity, and chain‑pairing analysis. Develop and validate analytical methods using advanced techniques including Surface Plasmon Resonance (SPR) and Biolayer Interferometry (BLI) for complex binding interactions and High‑Resolution Mass Spectrometry (HRMS) for structural characterisation, Drug‑to‑Antibody Ratio (DAR) determination...

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